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Shanthini Sockanathan, D.Phil.

Associated Investigator
E-mail: ssockan1@jhmi.edu

Dr. Shanthini Sockanathan is an associate professor of neuroscience at the Johns Hopkins University School of Medicine. Her research focuses on mechanistic control of neuronal and glial differentiation and function.


  • Nakamura M, Li Y, Choi BR, Matas-Rico E, Troncoso J, Takahashi C, Sockanathan S. GDE2-RECK controls ADAM10 alpha-secretase-mediated cleavage of amyloid precursor protein. Sci Transl Med. 2021;13: eabe6178.
  • Park S, Lee C, Sabharwal P, Zhang M, Meyers C, Sockanathan S. “GDE2 Promotes Neurogenesis by Glycosylphosphatidylinositol-Anchor Cleavage of Reck”. Science 339:324-339. 2013
  • Rodriguez M, Choi J, Park S, Sockanathan S. “Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation”. Development 2012 Oct; 139(20):3870-9. Epub 2012 Sep 5
  • Sabharwal P, Lee C, Park S, Rao M, Sockanathan S. “GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling”. Neuron. 2011 Sep 22; 71(6):1058-70. Epub 2011 Sep 21.