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Shanthini Sockanathan, D.Phil.

Associated Investigator
E-mail: [email protected]

Dr. Shanthini Sockanathan is an associate professor of neuroscience at the Johns Hopkins University School of Medicine. Her research focuses on mechanistic control of neuronal and glial differentiation and function.


  • Nakamura M, Li Y, Choi BR, Matas-Rico E, Troncoso J, Takahashi C, Sockanathan S. GDE2-RECK controls ADAM10 alpha-secretase-mediated cleavage of amyloid precursor protein. Sci Transl Med. 2021;13: eabe6178.
  • Park S, Lee C, Sabharwal P, Zhang M, Meyers C, Sockanathan S. “GDE2 Promotes Neurogenesis by Glycosylphosphatidylinositol-Anchor Cleavage of Reck”. Science 339:324-339. 2013
  • Rodriguez M, Choi J, Park S, Sockanathan S. “Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation”. Development 2012 Oct; 139(20):3870-9. Epub 2012 Sep 5
  • Sabharwal P, Lee C, Park S, Rao M, Sockanathan S. “GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling”. Neuron. 2011 Sep 22; 71(6):1058-70. Epub 2011 Sep 21.