Johns Hopkins Medicine

Alzheimer's Disease Research Center

Constantine G. Lyketsos, M.D., M.H.S.

Dr. Lyketsos

ADRC Associate Director
Clinical Core Leader
Education Core Co-Leader

Dr. Lyketsos is the Elizabeth Plank Althouse Professor for Alzheimer's Research. He is the Chair of Psychiatry at the Johns Hopkins Bayview Medical Center.

Dr. Lyketsos' research interests include the epidemiology of dementia, the epidemiology and treatment of neuropsychiatric disorders in dementia, and the etiology and effect of mood disorders occurring in patients with Alzheimer's.


  • Targum SD, Fosdick L, Drake KE, Rosenberg PB, Burke AD, Wolk DA, Foote KD, Asaad WF, Sabbagh M, Smith GS, Lozano AM, Lyketsos CG. Effect of age on clinical trial outcome in participants with probable Alzheimer’s disease. J Alzheimers Dis. 2021; 82:1243-1257.
  • Wise E, Rosenberg P, Lykestsos C, Leoutsakos J. Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers. Alzheimers Dement, 2019; 11: 333-339.
  • Ismail Z, Aquiera-Ortiz L, Brodaty H, Cieslak A, Cummings J, Fischer C, Gauthier S, Geda Y, Hermann N, Kanji J, Lanctot K, Miller D, Mortby M, Onyike C, Rosenberg P, Smith E, Smith G, Sultzer D, Lyketsos C. The Mild Behavioral Impairment Checklist (MBI-C): A rating scale for neuropsychiatric symptoms in pre-dementia populations. J Alzheimers Dis 2017; 56: 929-938.
  • Schneider L, Frangakis C, Drye L, Devanand D, Marano C, Mintzer M, Mulsant B, Munro C, Newall J, Pawluczyk S, Pelton G, Pollock B, Porsteinsson A, Rabins P, Rein L, Rosenberg P, Shade D, Weinstraub D, Yesavage J, Lyketsos C. Heterogeneity of treatment response to citalopram for patients with Alzheimer’s disease with aggression or agitation: The CitAD Randomized Clinical Trial. Am J Psychiatry, 2016; 173: 465-472.


Primary Appointment in Psychiatry & Behavioral Sciences