Johns Hopkins Medicine

Alzheimer's Disease Research Center

BIOCARD: Predictors of Cognitive Decline Among Normal Individuals

Principal Investigator: Marilyn S. Albert, Ph.D.

The goal of this study is to examine changes in cognition, brain structure and brain function during the earliest phases of Alzheimer's disease. Evaluations include: clinical and cognitive assessments, blood draws, brain imaging (magnetic resonance imaging scans and positron emission tomography scans) and collection of cerebrospinal fluid. Information about lifestyle factors, such as leisure activities and sleep, are also examined. Participants are cognitively normal when they are enrolled, and are followed annually, in order to track changes in these measures over time.

For more information, contact Maura Grega at 410-446-6161 or