Johns Hopkins Medicine

Alzheimer's Disease Research Center

Atherosclerosis in Communities - Neurocognitive Study

Principal Investigator: Joseph Coresh, M.D.

The goal of this study is to determine if late-life cognitive impairment and dementia are associated with midlife vascular risk factors. This is a multidisciplinary, multi-center prospective study of 15,792 black and white, men and women, who were aged 45-64 when they were first examined in 1987. The proposed study emphasizes the impact of mid-life vascular risks on subsequent mild cognitive impairment (MCI) and dementia because of the potential that risk-modification may lower the prevalence of MCI or dementia in late life.

For more information contact Joseph Coresh at